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Report on the 1987 MacArthur Foundation Network I Methodology Workshop

Helena Chmura Kraemer, PhD; Jennifer P. Pruyn, PhD

Arch Gen Psychiatry. 1990;47(12):1163-1169.

Abstract
• The second annual MacArthur Foundation Network I Methodology Workshop focused on the different approaches to implementing randomized controlled clinical trials (RCTs) and the situations in which each approach seems to be most appropriate. We reviewed the advantages and disadvantages of various approaches (single-site RCTs, multisite collaborative RCTs, multiple single-site RCTs, and meta-analysis of existing RCTs), and we make recommendations based on these considerations proposed.

Author Affiliations
From the Department of Psychiatry and Behavioral Sciences, Stanford (Calif) University.

Footnotes
Accepted for publication March 19, 1990.

Reprint requests to Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305 (Dr Kraemer).

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