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Contrast Detection in Schizophrenia
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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In their study, Chen et al1 presented new data concerning motion perception disturbances in schizophrenia. Using contrast sensitivity measurements in different experimental paradigms, the authors demonstrated that patients with schizophrenia displayed a specific deficit of motion perception, whereas other visual functions, such as orientation and contrast detection, were preserved. However, the question of medication was not addressed in this study, which makes the final interpretation difficult.
It is well established that dopaminergic deficiency in the visual system dominantly and specifically disrupts spatiotemporal contrast sensitivity functions.2 There is some evidence that this impairment is most pronounced for the transient visual channels, which are related to the processing of stimuli with low-spatial and high-temporal frequencies.3 Therefore, studies investigating contrast-sensitivity functions in patients with schizophrenia can be specifically confounded by uncontrolled antidopaminergic medication effects.
For example, Slaghuis4 found impaired contrast sensitivity in patients given medication when no motion discrimination was included. In contrast, . . . [Full Text of this Article]
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