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The Effects of Olive Oil on 3 Fatty Acids and Mood Disorders

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with interest the article by Stoll et al¹ on the benefits of 3 fatty acids on the short-term course of illness in bipolar disorder. The treatment group in this trial received the 3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid. The results are therefore consistent with the membrane phospholipid model of Horrobin,² dating from more than 20 years ago, and with the finding by both Peet and colleagues^3-4 and Maes and colleagues⁵ of depletion of 3 polyunsaturated fatty acid levels (particularly docosahexaenoic acid) in erythrocyte membranes of patients with depressive disorder; indeed, the first group has also found that severity of unipolar depression negatively correlates with both erythrocyte membrane 3 polyunsaturated fatty acid levels and dietary intake of these fatty acids.⁶

However, we would question the use of olive oil as a placebo in the present study. Dietary intake of olive oil may itself lead to an . . . [Full Text of this Article]

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