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Hypomania Associated With 3 Fatty Acids

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I would like to report a case of a 35-year-old woman with a history of major depressive disorder who developed symptoms of hypomania on starting an over-the-counter preparation of 3 fatty acids. The patient had a long history of several depressive episodes; however, she had not been receiving any antidepressants for 8 months. She was told by a friend that this specific product based on docosahexanoic acid (DHA) and eicosapentanoic acid (EPA) could be helpful with her mood. Although she did not have any symptoms suggesting a relapse, she started taking the 3 fatty acids preparation (2 capsules 3 times a day, containing 330 mg of DHA and 220 mg of EPA). Within 5 days, her behavior began to change and she became markedly disinhibited, elated, overfamiliar toward men, overactive, and expressing grandiose ideation. She was brought in by her family for an evaluation at the end of the first . . . [Full Text of this Article]

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Omega-3 Fatty Acids and Mood Disorders
Parker et al.
Am. J. Psychiatry 2006;163:969-978.
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