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Ellen Leibenluft, MD

Arch Gen Psychiatry. 2008;65(10):1122-1124.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Extending previous seminal work on pediatric bipolar disorder (BD), Geller et al¹ present the first longitudinal study following up a large sample of youth diagnosed with pediatric BD into adulthood. Beginning when the subjects had a mean (SD) age of 11.1 (2.6) years, the investigators followed up 115 patients with BD for 8 years, at which time 54 patients were older than 18 years. Of these, 44% had a manic episode after age 18 years, as ascertained by the Washington University in St Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS), suggesting continuity with previously observed symptoms. Morbidity, in terms of weeks spent ill, was extremely high, and 35.2% had substance abuse disorders. Attrition in the study was remarkably low.

Just as the children in this important study have matured over the last decade, so has research on pediatric BD. PubMed listings indicate that, from 1986 to . . . [Full Text of this Article]

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Child Bipolar I Disorder: Prospective Continuity With Adult Bipolar I Disorder; Characteristics of Second and Third Episodes; Predictors of 8-Year Outcome
Barbara Geller, Rebecca Tillman, Kristine Bolhofner, and Betsy Zimerman
Arch Gen Psychiatry. 2008;65(10):1125-1133.
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