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Citalopram Treatment in Children With Autism Spectrum Disorders and High Levels of Repetitive Behavior
Fred R. Volkmar, MD
Arch Gen Psychiatry. 2009;66(6):581-582.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Interest in autism and autism spectrum disorders (ASDs) has increased dramatically over the past decade.1 The convergence of approaches to diagnosis that are based on the DSM-IV and International Statistical Classification of Diseases, 10th Revision, fostered this effort, as did a major and sustained increase in federal funding—stimulated in large part by increasing pressure from parents. This interest has extended to treatment programs as well. For example, the report "Educating Young Children With Autism," from the National Research Council, summarized the importance of early and sustained intervention for improving long-term outcomes.2-3 A growing body of research has also demonstrated a high rate of comorbid conditions that lead to additional functional impairment.4-5
Corresponding to this general increase in research has been a focus on treatment research. Unfortunately, pharmacological intervention studies have often been hampered by small sample sizes and ambiguous results. A notable exception (and a . . . [Full Text of this Article] AUTHOR INFORMATION
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Lack of Efficacy of Citalopram in Children With Autism Spectrum Disorders and High Levels of Repetitive Behavior: Citalopram Ineffective in Children With Autism
Bryan H. King, Eric Hollander, Linmarie Sikich, James T. McCracken, Lawrence Scahill, Joel D. Bregman, Craig L. Donnelly, Evdokia Anagnostou, Kimberly Dukes, Lisa Sullivan, Deborah Hirtz, Ann Wagner, Louise Ritz, and for the STAART Psychopharmacology Network
Arch Gen Psychiatry. 2009;66(6):583-590.
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Citalopram Ineffective for Children with Autism Spectrum Disorders
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